بررسی پاسخ ایمنی سلولی پس از تزریق داخل ماهیچه ای پلاسمید pcdna3.1+pa در موش

بررسی پاسخ تکثیری لنفوسیت‌های طحالی حاصل از تزریق پلاسمید کد کننده E7-HPV16 در مدل موش توموری پاپیلوماویروس

Background & Objective: Human papillomavirus (HPV) oncoproteins, including E6 and E7 are constitutively expressed in cervical cancer cells. These proteins are ideal targets to be used for developing therapeutic vaccines against existing HPV-associated carcinomas. The aim of this study was to measure the proliferation response rate of splenic lymphocytes derived from E7-HPV16 encoding plasmid in...

اثر کاروتنوئید‏‏های محلول در آب زعفران بر پاسخ ایمنی سلولی در موش BALB/c

  Introduction: Saffron (thread-like reddish colored stigmas of Crocus sativus L. flowers) was used in traditional medicine for cancers and infectious diseases. Recently, anti-tumor, cytotoxic, anti-mutagenesis and antioxidant activities of saffron metabolites, especially its carotenoids (crocins and crocetin), have been reported.   Objective: Since the saffron is used as a spice for food flavo...

سنجش پاسخ ایمنی نوزادان به تزریق داخل جلدی با دوز پایین واکسن هپاتیت B

Background and purpose : Hepatitis B viral infection (NBÏ) and its sequelae are a major worldwide health problem. The most effective way to contral and prevent HBÏ is univerral immunization with hepatitis B vaccine (HBÏ). But the most limitation of it is inadequate resource. The aim of this study is to evaluate the immunogenitity of low dose immtradermal (ÏD) HBV, according to routine intramu...

تعدیل پاسخ ایمنی سلولی متعاقب سوختگی در مدل حیوانی موش Balb/c

Background: Infection is the major cause of death in thermal injury patients. Severe suppression of the immune system is the major cause of infection following burn injury. The aim of this study was to modulate the cell-mediated immune response by the use of cimetidine and pyrimethamine in an animal burn model. Materials and Methods: Male Balb/c mice were anesthetized, and given a 10% total ...

تولید آنتی بادی بر ضد IgG انسانی در خرگوش: مقایسه دو روش تزریق داخل ماهیچه ای و زیر جلدی

Background and objectives: Anti-human immunoglobulin G (IgG) antibody is produced against human IgG in various laboratory animals. The present study tried not only to produce anti-human IgG, but also to assess different antigen injection techniques leading to optimal production of anti-human globulin.Methods: The antibody was separated from human serum using precipitation method with sodium sul...

بررسی وضعیت پاسخ ایمنی گوساله های آغوز نخورده کمتر از شش ماه سن پس از تزریق واکسن طاعون گاوی و مطالعه در مورد پیدایش شکیبایی ایمنی